While the rule of threes can identify when a baby has colic, and despite a wealth of research on colic; there is no single definitive widely agreed to cause for colic. We do know that very often bouts of colic occur in the late afternoons and evenings. It is possible that baby is already tired or restless and this makes the symptoms of colic more pronounced at nighttime. Mommy’s Bliss® Night Time Gripe Water helps with all these symptoms by promoting relaxation and sleep as well as easing baby’s stomach discomfort.